翻訳と辞書 Words near each other ・ Cycling at the 1964 Summer Olympics – Men's sprint ・ Cycling at the 1964 Summer Olympics – Men's tandem ・ Cycling at the 1964 Summer Olympics – Men's team pursuit ・ Cycling at the 1964 Summer Olympics – Men's team time trial ・ Cycling at the 1967 Pan American Games ・ Cycling at the 1968 Summer Olympics ・ Cycling at the 1968 Summer Olympics – Men's 1000m time trial ・ Cycling at the 1968 Summer Olympics – Men's individual pursuit ・ Cycling at the 1968 Summer Olympics – Men's individual road race ・ Cycling at the 1968 Summer Olympics – Men's sprint ・ Cycling at the 1968 Summer Olympics – Men's tandem ・ Cycling at the 1968 Summer Olympics – Men's team pursuit ・ Cycling at the 1968 Summer Olympics – Men's team time trial ・ Cycling at the 1970 Asian Games ・ Cyclin E ・ Cyclin E1 ・ Cyclin E2 ・ Cyclin H ・ Cyclin K ・ Cyclin O ・ Cyclin T1 ・ Cyclin T2 ・ Cyclin-dependent kinase ・ Cyclin-dependent kinase 1 ・ Cyclin-dependent kinase 10 ・ Cyclin-dependent kinase 2 ・ Cyclin-dependent kinase 3 ・ Cyclin-dependent kinase 4 ・ Cyclin-dependent kinase 5 ・ Cyclin-dependent kinase 6 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Cyclin E1 ： ウィキペディア英語版 Cyclin E1 G1/S-specific cyclin-E1 is a protein that in humans is encoded by the ''CCNE1'' gene. == Function == The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Cyclin E1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.